"I continue to fine tune biochemical test options to streamline the testing process for maximal data while saving on OVERALL costs. So while one test may be more costly but addresses an important consideration, another test may be less expensive so that the composite of both is less of a financial burden. For instance a major concern I have had over the years has been the ability to identify H.pylori as well as other slow growing organisms. I believe that a DNA based GI test (GI Pathogen Plus Test) is the best diagnostic tool to determine the presence of H.pylori. Years ago a DNA based test for H.pylori was available, however that had not been the case for a number of years. In the interim I have tried a saliva test for H.pylori antibody as well as a stool test for H.pylori antigen. While less costly than the DNA test for H.pylori, these tests often give false negative results in my opinion, picking up more severe cases but missing low levels of H.pylori in the system. In addition another down side of the stool/saliva combination test was that many were not able to submit a sufficient sample of saliva to even obtain a result.

     Where almost half of those with autism may harbor H.pylori and over 1/3 of adults may also have this issue, I do feel that a reliable test that can detect low levels of H.pylori using DNA based methodology is critical. For these reasons I have discontinued the stool/saliva test and replaced it with the DNA based GI test (GI Pathogen Plus Test). 

     The downside of DNA based tests is that they only detect organisms that are being specifically tested with a precise DNA probe. Thus, this DNA based GI test will specifically detect H.pylori, as well as particular strains of E.coli, Shigella, Salmonella and Clostridia. But this test will not pick up any organisms for which there is no specific probe. For this reason, it is important to also run a more standard CSA to detect a larger range of microbes. The CSA will pick up any yeast or bacteria that will grow in a set incubation time. This allows for a much larger range of organisms that can be detected including many that I routinely see such as Klebsiella, Pseudomonas, Enterococcus, Virbrio, Yersinia, Staphylococcus, Streptococcus and a wide range of species of yeast. The CSA also looks at important markers for gut inflammation, digestion as well as gut pH. 

     The combination of a CSA which picks up a wide range of bacterial and yeast imbalances and other gut markers ALONG with the DNA GI test for H.pylori and other difficult to detect organisms is the most comprehensive combination of GI tests that have been available in years. I highly suggest that this combination of the CSA with the DNA GI test be seriously considered on a routine basis.

     In addition I have separated out the Parasite test, as a standalone option. There was confusion in terms of individuals sometimes running a parasite test with the CSA and other times not running it. In some cases individuals ran the more expensive combination test when that was not their intent. While the prior salive/stool combo test did look at some parasite markers, again the inability to get adequate saliva samples made that test ineffective in many cases. For this reason, I have chosen a lower cost standalone Parasite test. Those who have a higher than expected pH on a CSA and show no H.pylori on the DNA test should then consider the Parasite test. Or those who have had prior issues with parasites, have traveled to regions where parasites are prevalent or suspect parasites can run this standalone Parasite test. 

     To summarize, after searching and researching the best GI tests available, at this point I am very happy with the options we finally have available. I highly suggest the CSA along with the DNA based GI test for all. If this is not possible, then at the very least, run a CSA and if the gut pH on the CSA is either pH 7 or higher (ie 7.2, 7.4) or 5.8 or below (ie 5.6 etc), then consider the DNA based GI test to rule out H.pylori. If you have had a history of constant acid reflux, burping, bloating then run the DNA based GI test. If your suberic is very high on a MAP or Organic acid test, then consider the DNA based GI test. If you show moderate levels of bismuth on a HMT, FMTUTM in the absence of using Pepto-Bismol, then consider the DNA based GI test.

     In terms of testing for Parasites, those who are able to run a comprehensive set of GI tests should run the CSA, DNA based GI and the Parasite test. If you are not able to run all three, then again start with the CSA and if the gut pH is 7 or above the next step would be to run BOTH the DNA based GI test along with the Parasite test. It has been my experience that in most cases if the stool pH is 7 or higher that we find a positive indications of H.pylori and/or a positive test for parasites.

     Please know, that I continue to refine and fine tune tests, the supplement lists and how I approach the program in order to do the best possible job of aiding all of you in achieving optimal health." 

With love and hope for health always,


Disclaimer: The information expressed in this document does not constitute an attempt to practice medicine nor does it establish a doctor-patient relationship. This informational and educational purposes only. Statements made in this document have not been evaluated by the U.S. Food & Drug Administration (FDA). The information provided is not intended to diagnose, treat, cure any disease or be used as the basis for treating a particular symptom or disease. Any products discussed or endorsed are not intended to diagnose, treat, cure any diseases or be used as the basis for treating a particular symptom or disease.